Conventional denture fixatives work by thickening saliva between the denture and gum. The dentures hold only by suction. Being water soluble, these fixatives dissolve and lose their effectiveness within a short period of time. fittydent Denture Adhesive works in a completely new and different way: fittydent is worldwide the only denture adhesive that is non water-soluble. That means it will not wash out while eating or drinking. fittydent provides an extremely strong bonding effect, thus preventing dentures from slipping or sliding!